Manitoba · Grade 12

Biology, Grade 12 (Biology 40S)

Manitoba’s Grade 12 science course, from Understanding Biological Inheritance to Conservation of Biodiversity.

Units
5
Lessons
14
Skills
45
Provincial exam
None
Official curriculum
Manitoba Education

Unit by unit

Every skill in the course, with its official code.

Unit 1 · 12 skills

Understanding Biological Inheritance

Mendel and Genetic Crosses

  • Outline Gregor Mendel's principles of inheritance

    I can outline Mendel's principles of dominance, segregation and independent assortment, and explain why they matter for understanding heredity.

    Official code: B12-1-01

  • Explain what is meant by the terms heterozygous and homozygous

    I can explain what homozygous and heterozygous mean and use the terms to describe genotypes.

    Official code: B12-1-02

  • Distinguish between genotype and phenotype, and use these terms in discussing genetic crosses

    I can distinguish between genotype and phenotype and use both terms correctly when discussing the outcomes of genetic crosses.

    Official code: B12-1-03

Punnett Squares and Inheritance Patterns

  • Use Punnett squares to solve a variety of autosomal inheritance problems

    I can use Punnett squares to solve monohybrid, dihybrid and testcross problems and justify my answers with the correct terms.

    Official code: B12-1-04

  • Describe examples of and solve problems involving traits that do not follow a dominant-recessive pattern

    I can describe examples of incomplete dominance, codominance, multiple alleles and lethal genes, and solve problems involving them.

    Official code: B12-1-05

Sex Determination, Sex-Linkage, and Pedigrees

  • Explain the basis for sex determination in humans

    I can explain how the X and Y chromosomes determine sex in humans.

    Official code: B12-1-06

  • Describe examples of and solve problems involving sex-linked genes

    I can describe sex-linked conditions such as colour-blindness, hemophilia and Duchenne muscular dystrophy, and solve problems involving sex-linked genes.

    Official code: B12-1-07

  • Use pedigree charts to illustrate the inheritance of genetically determined traits in a family tree

    I can draw and read pedigree charts, decide how a trait is inherited, and find the probability of a child having the trait.

    Official code: B12-1-08

  • Discuss ethical issues that may arise as a result of genetic testing

    I can discuss the ethical issues that genetic testing for inherited conditions can raise for individuals, families and society.

    Official code: B12-1-09

Meiosis and Chromosome Mutations

  • Discuss the role of meiosis and sexual reproduction in producing genetic variability

    I can explain how meiosis and sexual reproduction, through crossing over and random assortment, produce genetically varied offspring.

    Official code: B12-1-10

  • Explain how chromosome mutations may arise during meiosis

    I can explain how chromosome mutations such as nondisjunction arise during meiosis.

    Official code: B12-1-11

  • Identify monosomy and trisomy chromosome mutations from karyotypes

    I can identify monosomies and trisomies such as Down, Turner and Klinefelter syndromes from karyotypes.

    Official code: B12-1-12

The official wording · 12 outcomes
B12-1-01
Outline Gregor Mendel's principles of inheritance, stating their importance to the understanding of heredity
B12-1-02
Explain what is meant by the terms heterozygous and homozygous
B12-1-03
Distinguish between genotype and phenotype, and use these terms appropriately when discussing the outcomes of genetic crosses
B12-1-04
Use Punnett squares to solve a variety of autosomal inheritance problems, and justify the results using appropriate terminology
B12-1-05
Describe examples of and solve problems involving the inheritance of phenotypic traits that do not follow a dominant-recessive pattern
B12-1-06
Explain the basis for sex determination in humans
B12-1-07
Describe examples of and solve problems involving sex-linked genes
B12-1-08
Use pedigree charts to illustrate the inheritance of genetically determined traits in a family tree and to determine the probability of certain offspring having particular traits
B12-1-09
Discuss ethical issues that may arise as a result of genetic testing for inherited conditions or disorders
B12-1-10
Discuss the role of meiosis and sexual reproduction in producing genetic variability in offspring
B12-1-11
Explain how chromosome mutations may arise during meiosis
B12-1-12
Identify monosomy and trisomy chromosome mutations from karyotypes

Key ideas

  1. Mendel crossed pea plants and counted thousands of offspring; he knew nothing of chromosomes, genes or DNA and worked out his principles from the numbers alone, and his work, ignored for 35 years and rediscovered in 1900, became the foundation of genetics.

  2. A Punnett square lists one parent's possible gametes across the top and the other parent's down the side; each box is one possible offspring, and each box is equally likely.

  3. Humans have 22 pairs of autosomes and one pair of sex chromosomes: XX in females and XY in males.

  4. Meiosis is a reduction division: a diploid cell with 46 chromosomes (23 pairs) produces four haploid gametes with 23 each, so fertilization restores 46 instead of doubling the number every generation.

  5. Principle of dominance: when an organism carries two different factors (alleles) for a trait, one, the dominant allele, can hide the other, the recessive allele.

Watch out for

  • Thinking Mendel knew about genes and chromosomes, when he worked out his principles by counting offspring decades before chromosomes were linked to heredity.
  • Thinking a 3:1 ratio means exactly three of every four offspring will show the dominant trait, when each offspring has a 3 in 4 chance and small families vary.
  • Thinking the mother's egg decides the baby's sex, when every egg carries an X and the sperm carries either an X or a Y.

Every skill’s key ideas, worked examples and checks are in MapleMind.Practise this unit

Unit 2 · 10 skills

Mechanisms of Inheritance

DNA Structure and Replication

  • Outline significant scientific contributions and discoveries that led to the current understanding of DNA

    I can outline the discoveries that led to our understanding of DNA's structure and function, and how collaboration and competition shaped them.

    Official code: B12-2-01

  • Describe the structure of a DNA nucleotide

    I can describe the structure of a DNA nucleotide: a deoxyribose sugar, a phosphate group and a nitrogenous base.

    Official code: B12-2-02

  • Describe the structure of a DNA molecule

    I can describe the structure of a DNA molecule, including the double helix, base pairing and genes.

    Official code: B12-2-03

  • Describe the process of DNA replication

    I can describe how DNA replicates, using the terms template, semi-conservative replication and enzymes.

    Official code: B12-2-04

From Gene to Protein

  • Compare DNA and RNA in terms of their structure, use, and location in the cell

    I can compare DNA and RNA by their structure, their use and where they are found in the cell.

    Official code: B12-2-05

  • Outline the steps involved in protein synthesis

    I can outline protein synthesis, from transcription of a gene into mRNA to translation into a protein at a ribosome.

    Official code: B12-2-06

Mutation and Gene Technology

  • Relate the consequences of gene mutation to the final protein product

    I can relate a gene mutation to its effect on the final protein, using point mutations and frameshift mutations as examples.

    Official code: B12-2-07

  • Discuss implications of gene mutation for genetic variation

    I can discuss how gene mutations create new alleles and add to genetic variation.

    Official code: B12-2-08

  • Investigate an issue related to the application of gene technology in bioresources

    I can investigate an issue about gene technology in bioresources, including the technology, its economic implications and different perspectives.

    Official code: B12-2-09

  • Investigate an issue related to the application of gene technology in humans

    I can investigate an issue about gene technology in humans, including the technology, its ethical and legal implications and different perspectives.

    Official code: B12-2-10

The official wording · 10 outcomes
B12-2-01
Outline significant scientific contributions/discoveries that led to the current understanding of the structure and function of the DNA molecule
B12-2-02
Describe the structure of a DNA nucleotide
B12-2-03
Describe the structure of a DNA molecule
B12-2-04
Describe the process of DNA replication
B12-2-05
Compare DNA and RNA in terms of their structure, use, and location in the cell
B12-2-06
Outline the steps involved in protein synthesis
B12-2-07
Relate the consequences of gene mutation to the final protein product
B12-2-08
Discuss implications of gene mutation for genetic variation
B12-2-09
Investigate an issue related to the application of gene technology in bioresources
B12-2-10
Investigate an issue related to the application of gene technology in humans

Key ideas

  1. Understanding DNA took about 85 years and many scientists: Miescher isolated it from cell nuclei in 1869, Levene showed it is a chain of nucleotides, and Sutton, Boveri and Morgan tied genes to chromosomes.

  2. DNA is double-stranded and contains the sugar deoxyribose and the base thymine; RNA is usually single-stranded, contains ribose, and has uracil in place of thymine.

  3. A gene mutation is a change in the base sequence of DNA; because the base sequence decides the amino acid sequence, a mutation can change the protein.

  4. Experiments proved DNA is the genetic material: Griffith found that bacteria could be transformed (1928), Avery, MacLeod and McCarty, two of them born in Canada, identified the transforming substance as DNA (1944), and Hershey and Chase confirmed it with labelled viruses (1952).

  5. DNA stays in the nucleus (and the mitochondria) and stores the genetic code long-term; RNA is made in the nucleus and does most of its work in the cytoplasm, carrying out the instructions.

Watch out for

  • Thinking Watson and Crick discovered DNA, when it was discovered in 1869 and they worked out its structure in 1953 using other scientists' data.
  • Thinking RNA contains thymine, when RNA has uracil in its place.
  • Thinking every change to a DNA base changes the protein, when many point mutations are silent because several codons code for the same amino acid.

Every skill’s key ideas, worked examples and checks are in MapleMind.Practise this unit

Unit 3 · 12 skills

Evolutionary Theory and Biodiversity

Darwin and Natural Selection

  • Define the term evolution, explaining how evolution has led to biodiversity by altering populations

    I can define evolution as a change in a population's gene pool and explain how it has produced biodiversity by changing populations, not individuals.

    Official code: B12-3-01

  • Describe and explain the process of discovery that led Charles Darwin to formulate his theory of evolution by natural selection

    I can describe and explain how the voyage of the Beagle, the South American fossils, the Galapagos Islands and the work of other scientists led Darwin to his theory of natural selection.

    Official code: B12-3-02

  • Outline the main points of Darwin's theory of evolution by natural selection

    I can outline the main points of Darwin's theory: overproduction, competition, variation, adaptation, natural selection and speciation.

    Official code: B12-3-03

  • Demonstrate, through examples, what the term fittest means in the phrase “survival of the fittest.”

    I can demonstrate, with examples, that 'fittest' means best suited to the environment and most successful at reproducing.

    Official code: B12-3-04

Selection and Changing Gene Pools

  • Explain how natural selection leads to changes in populations

    I can explain how natural selection changes populations, using examples such as industrial melanism and resistance to antibiotics and pesticides.

    Official code: B12-3-05

  • Describe how disruptive, stabilizing, and directional natural selection act on variation

    I can describe how stabilizing, directional and disruptive selection act on the variation in a population.

    Official code: B12-3-06

  • Distinguish between natural selection and artificial selection

    I can distinguish between natural selection and artificial selection.

    Official code: B12-3-07

  • Outline how scientists determine whether a gene pool has changed

    I can outline how scientists use the conditions for genetic equilibrium and the Hardy-Weinberg equations to tell whether a gene pool has changed.

    Official code: B12-3-08

  • Discuss how genetic variation in a gene pool can be altered

    I can discuss how natural selection, gene flow, genetic drift, non-random mating and mutation alter the genetic variation in a gene pool.

    Official code: B12-3-09

Speciation and the Pace of Evolution

  • Describe how populations can become reproductively isolated

    I can describe how populations become reproductively isolated through geographic isolation, niche differentiation, behaviour and physiology.

    Official code: B12-3-10

  • With the use of examples, differentiate between convergent and divergent evolution (adaptive radiation)

    I can differentiate between convergent evolution and divergent evolution (adaptive radiation) with examples, using homologous and analogous structures.

    Official code: B12-3-11

  • Distinguish between the two models for the pace of evolutionary change: punctuated equilibrium and gradualism

    I can distinguish between gradualism and punctuated equilibrium as models for the pace of evolutionary change.

    Official code: B12-3-12

The official wording · 12 outcomes
B12-3-01
Define the term evolution, explaining how evolution has led to biodiversity by altering populations and not individuals
B12-3-02
Describe and explain the process of discovery that led Charles Darwin to formulate his theory of evolution by natural selection
B12-3-03
Outline the main points of Darwin's theory of evolution by natural selection
B12-3-04
Demonstrate, through examples, what the term fittest means in the phrase “survival of the fittest.”
B12-3-05
Explain how natural selection leads to changes in populations
B12-3-06
Describe how disruptive, stabilizing, and directional natural selection act on variation
B12-3-07
Distinguish between natural selection and artificial selection
B12-3-08
Outline how scientists determine whether a gene pool has changed, according to the criteria for genetic equilibrium
B12-3-09
Discuss how genetic variation in a gene pool can be altered
B12-3-10
Describe how populations can become reproductively isolated
B12-3-11
With the use of examples, differentiate between convergent evolution and divergent evolution (adaptive radiation)
B12-3-12
Distinguish between the two models for the pace of evolutionary change: punctuated equilibrium and gradualism

Key ideas

  1. Evolution is a change in the frequencies of alleles in a population's gene pool over generations: populations evolve, individuals do not.

  2. Natural selection changes a population when individuals with a heritable trait survive and reproduce more than others, so the alleles for that trait become more common in the next generation.

  3. A species is a group of populations whose members can interbreed and produce fertile offspring; new species form when populations become reproductively isolated.

  4. A gene pool is all the alleles of all the genes in a population; a genome is the complete set of DNA, all the genes, of one individual or one species.

  5. In industrial melanism, dark peppered moths were rare in England before the 1800s, became common as soot darkened tree trunks and birds ate the easily seen pale moths, and became rare again after clean-air laws.

Watch out for

  • Thinking individual organisms evolve during their lifetimes, when evolution is a change in a population's allele frequencies over generations.
  • Thinking the antibiotic causes bacteria to become resistant, when resistant bacteria already exist and the antibiotic kills the others, so the resistant ones take over.
  • Thinking populations must be separated by a physical barrier to become separate species, when behaviour, timing, habitat or chromosome changes can isolate them in the same place.

Every skill’s key ideas, worked examples and checks are in MapleMind.Practise this unit

Unit 4 · 7 skills

Organizing Biodiversity

Biodiversity and Defining Species

  • Define the concept of biodiversity in terms of ecosystem, species and genetic diversity

    I can define biodiversity in terms of ecosystem diversity, species diversity and genetic diversity.

    Official code: B12-4-01

  • Explain why it is difficult to determine a definition of species

    I can explain why it is difficult to define a species, using hybrids, variation within species and non-interbreeding subpopulations.

    Official code: B12-4-02

Classification and Its Evidence

  • Describe the dynamic nature of classification

    I can describe how classification keeps changing, including different classification systems and current debates.

    Official code: B12-4-03

  • Describe types of evidence used to classify organisms and determine evolutionary relationships

    I can describe how fossils, morphology, embryology, biochemistry and DNA are used to classify organisms and work out their evolutionary relationships.

    Official code: B12-4-04

Domains, Kingdoms, and Evolutionary Trends

  • Compare the characteristics of the domains of life

    I can compare the characteristics of the three domains of life: Bacteria, Archaea and Eukarya.

    Official code: B12-4-05

  • Compare the characteristics of the kingdoms in the Eukarya domain

    I can compare the kingdoms of the domain Eukarya by cell structure, major mode of nutrition, cell number and motility.

    Official code: B12-4-06

  • Investigate an evolutionary trend in a group of organisms

    I can investigate an evolutionary trend in a group of organisms, such as vascular tissue in plants, the move of animals onto land, or human evolution.

    Official code: B12-4-07

The official wording · 7 outcomes
B12-4-01
Define the concept of biodiversity in terms of ecosystem, species, and genetic diversity
B12-4-02
Explain why it is difficult to determine a definition of species
B12-4-03
Describe the dynamic nature of classification
B12-4-04
Describe types of evidence used to classify organisms and determine evolutionary relationships
B12-4-05
Compare the characteristics of the domains of life
B12-4-06
Compare the characteristics of the kingdoms in the Eukarya domain
B12-4-07
Investigate an evolutionary trend in a group of organisms

Key ideas

  1. Biodiversity is the variety of life in an area, measured at three levels: ecosystem diversity, species diversity and genetic diversity.

  2. Linnaeus sorted organisms into nested groups, from kingdom down to species, by body form, and gave each species a two-part (binomial) name, such as Ursus maritimus for the polar bear.

  3. Life is grouped into three domains, proposed by Carl Woese in 1990 from comparisons of ribosomal RNA: Bacteria, Archaea and Eukarya.

  4. Ecosystem diversity is the variety of habitats and communities, such as Manitoba's tall-grass prairie, boreal forest, wetlands and tundra; genetic diversity is the variety of alleles within one species.

  5. Classification has changed as evidence grew: from two kingdoms (plants and animals) to five or six, and since 1990 to three domains above the kingdoms, as microscopes and DNA revealed new differences.

Watch out for

  • Thinking biodiversity means only the number of species, when it also includes the genetic diversity within species and the variety of ecosystems.
  • Thinking the classification system is fixed and final, when it is revised as new evidence, especially from DNA, appears.
  • Thinking archaea are just a kind of bacteria, when they are a separate domain with different cell walls, membranes and RNA.

Every skill’s key ideas, worked examples and checks are in MapleMind.Practise this unit

Unit 5 · 4 skills

Conservation of Biodiversity

Conserving Biodiversity

  • Discuss a variety of reasons for maintaining biodiversity

    I can discuss a variety of reasons for maintaining biodiversity, including a diverse gene pool, economic value and the sustainability of ecosystems.

    Official code: B12-5-01

  • Describe strategies used to conserve biodiversity

    I can describe strategies used to conserve biodiversity, such as habitat protection, wildlife corridors, species preservation programs and public education.

    Official code: B12-5-02

  • Select and use appropriate tools or procedures to determine and monitor biodiversity in an area

    I can select and use tools and procedures such as dichotomous keys, quadrats, transects and mark and recapture to determine and monitor biodiversity in an area.

    Official code: B12-5-03

  • Investigate an issue related to the conservation of biodiversity

    I can investigate an issue related to conserving biodiversity, such as water quality in Lake Winnipeg or hydroelectric development, and recommend a course of action.

    Official code: B12-5-04

The official wording · 4 outcomes
B12-5-01
Discuss a variety of reasons for maintaining biodiversity
B12-5-02
Describe strategies used to conserve biodiversity
B12-5-03
Select and use appropriate tools or procedures to determine and monitor biodiversity in an area
B12-5-04
Investigate an issue related to the conservation of biodiversity

Key ideas

  1. A diverse gene pool lets a species survive disease and change: genetically varied crops and their wild relatives hold alleles for resistance to new pests and diseases.

  2. Biodiversity has economic value: food, timber, fish, medicines (ASA was developed from salicin, a compound in willow bark), tourism, and services such as pollination and water filtration.

  3. Diverse ecosystems are more sustainable: when many species fill each role, the ecosystem keeps working if one species declines.

  4. People value nature for its uses (utilitarian value) and for its own sake (inherent value), including cultural and spiritual value, such as the sacred value of sweetgrass to First Nations peoples.

  5. Habitat conservation protects or restores whole ecosystems, through parks and protected areas, wetland restoration and sustainable forest management, which conserves many species at once.

Watch out for

  • Thinking biodiversity only matters for species that are useful to people, when all species contribute to ecosystem stability and many are valued for themselves.
  • Thinking that losing a few species makes no difference to an ecosystem, when each loss reduces its ability to recover from change.
  • Thinking a species with a large population is safe from extinction, when low genetic diversity can leave it unable to survive a new disease.

Every skill’s key ideas, worked examples and checks are in MapleMind.Practise this unit

The official curriculum

This page follows Manitoba’s own curriculum for Biology, Grade 12 (Biology 40S).

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Questions about Biology, Grade 12 (Biology 40S)

What is Biology, Grade 12 (Biology 40S)?

Manitoba’s Grade 12 science course: 5 units and 45 skills, from Understanding Biological Inheritance to Conservation of Biodiversity.

What units are in Biology, Grade 12 (Biology 40S)?

1. Understanding Biological Inheritance, 2. Mechanisms of Inheritance, 3. Evolutionary Theory and Biodiversity, 4. Organizing Biodiversity and 5. Conservation of Biodiversity.

Is there a provincial exam for Biology, Grade 12 (Biology 40S)?

No. Manitoba gives no provincial exam for Biology, Grade 12 (Biology 40S).

Can MapleMind help with Biology, Grade 12 (Biology 40S)?

Yes. MapleMind teaches every skill of Biology, Grade 12 (Biology 40S), step by step, with practice and checks, and its tutor answers questions about any of them. It’s free with daily limits, on iPhone, Android and the web.

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